Reassessment of recommended imipenem doses in febrile neutropenic patients with hematological malignancies.
Détails
ID Serval
serval:BIB_3C81678B0325
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Reassessment of recommended imipenem doses in febrile neutropenic patients with hematological malignancies.
Périodique
Antimicrobial Agents and Chemotherapy
ISSN
1098-6596
Statut éditorial
Publié
Date de publication
2009
Peer-reviewed
Oui
Volume
53
Numéro
2
Pages
785-787
Langue
anglais
Résumé
Imipenem plasma concentrations were analyzed in 57 febrile neutropenic patients using the NONMEM program. The recommended 2-g/day regimen achieved coverage of the most common bacteria (MIC(90) = 1 mg/liter) during the whole dosing interval in only 53% of patients. This goal was achieved in 90% of patients with 3 g/day.
Pubmed
Web of science
Open Access
Oui
Création de la notice
26/02/2009 16:28
Dernière modification de la notice
20/08/2019 13:32