Reassessment of recommended imipenem doses in febrile neutropenic patients with hematological malignancies.
Details
Serval ID
serval:BIB_3C81678B0325
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Reassessment of recommended imipenem doses in febrile neutropenic patients with hematological malignancies.
Journal
Antimicrobial Agents and Chemotherapy
ISSN
1098-6596
Publication state
Published
Issued date
2009
Peer-reviewed
Oui
Volume
53
Number
2
Pages
785-787
Language
english
Abstract
Imipenem plasma concentrations were analyzed in 57 febrile neutropenic patients using the NONMEM program. The recommended 2-g/day regimen achieved coverage of the most common bacteria (MIC(90) = 1 mg/liter) during the whole dosing interval in only 53% of patients. This goal was achieved in 90% of patients with 3 g/day.
Pubmed
Web of science
Open Access
Yes
Create date
26/02/2009 16:28
Last modification date
20/08/2019 13:32