Malignant blue naevus with distant subcutaneous metastasis

Détails

ID Serval
serval:BIB_39948EACC13C
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Etude de cas (case report): rapporte une observation et la commente brièvement.
Collection
Publications
Titre
Malignant blue naevus with distant subcutaneous metastasis
Périodique
Clinical and Experimental Dermatology
Auteur(s)
Boni  R., Panizzon  R., Huch Boni  R. A., Steinert  H., Dummer  R.
ISSN
0307-6938 (Print)
Statut éditorial
Publié
Date de publication
11/1996
Volume
21
Numéro
6
Pages
427-30
Notes
Case Reports
Journal Article --- Old month value: Nov
Résumé
Malignant blue naevus is a distinct but rarely documented variant of malignant melanoma, and we describe the triple recurrence of a suprapatellar cellular blue naevus over 12 years in a middle-aged woman. Staging investigations revealed a distant subcutaneous metastasis of the right thigh. Immunohistochemistry of the primary lesion and all recurrences showed S-100, HMB-45, NKI/C-3 and Ki-67 positive cells. However, non-malignant cellular blue naevi from five consecutive other patients were all Ki-67 negative. The change from negative to positive Ki-67 responsivity may therefore be a valuable marker of malignant and metastatic potential in early cellular blue naevi.
Mots-clé
Female Humans Immunohistochemistry Leg Magnetic Resonance Imaging Middle Aged Neoplasm Recurrence, Local/*pathology/radionuclide imaging Nevus, Blue/pathology/radionuclide imaging/*secondary Skin Neoplasms/*pathology/radionuclide imaging Soft Tissue Neoplasms/pathology/radionuclide imaging/*secondary Thigh Tomography, Emission-Computed
Pubmed
Web of science
Création de la notice
25/01/2008 16:54
Dernière modification de la notice
20/08/2019 13:29
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