Article: article from journal or magazin.
3DCoffee@igs: a web server for combining sequences and structures into a multiple sequence alignment.
Nucleic Acids Research
Web Server issue
Publication types: Journal Article
This paper presents 3DCoffee@igs, a web-based tool dedicated to the computation of high-quality multiple sequence alignments (MSAs). 3D-Coffee makes it possible to mix protein sequences and structures in order to increase the accuracy of the alignments. Structures can be either provided as PDB identifiers or directly uploaded into the server. Given a set of sequences and structures, pairs of structures are aligned with SAP while sequence-structure pairs are aligned with Fugue. The resulting collection of pairwise alignments is then combined into an MSA with the T-Coffee algorithm. The server and its documentation are available from http://igs-server.cnrs-mrs.fr/Tcoffee/.
Internet, Proteins/chemistry, Sequence Alignment, Sequence Analysis, Protein, Software
Web of science
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