Major histocompatibility complex-linked social signalling affects female fertility.

Détails

Ressource 1Télécharger: Burger et al. Proc B 2017.pdf (4062.10 [Ko])
Etat: Serval
Version: Author's accepted manuscript
ID Serval
serval:BIB_30EE7C2B84F4
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Major histocompatibility complex-linked social signalling affects female fertility.
Périodique
Proceedings. Biological sciences
Auteur(s)
Burger D., Thomas S., Aepli H., Dreyer M., Fabre G., Marti E., Sieme H., Robinson M.R., Wedekind C.
ISSN
1471-2954 (Electronic)
ISSN-L
0962-8452
Statut éditorial
Publié
Date de publication
06/12/2017
Peer-reviewed
Oui
Volume
284
Numéro
1868
Pages
20171824
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Résumé
Genes of the major histocompatibility complex (MHC) have been shown to influence social signalling and mate preferences in many species, including humans. First observations suggest that MHC signalling may also affect female fertility. To test this hypothesis, we exposed 191 female horses ( <i>Equus caballus</i> ) to either an MHC-similar or an MHC-dissimilar stimulus male around the time of ovulation and conception. A within-subject experimental design controlled for non-MHC-linked male characteristics, and instrumental insemination with semen of other males ( <i>n</i> = 106) controlled for potential confounding effects of semen or embryo characteristics. We found that females were more likely to become pregnant if exposed to an MHC-dissimilar than to an MHC-similar male, while overall genetic distance to the stimulus males (based on microsatellite markers on 20 chromosomes) had no effect. Our results demonstrate that early pregnancy failures can be due to maternal life-history decisions (cryptic female choice) influenced by MHC-linked social signalling.
Mots-clé
Animals, Female, Fertility, Horses/physiology, Major Histocompatibility Complex, Mating Preference, Animal, Reproduction, cryptic female choice, female reproductive strategy, fertility, major histocompatibility complex, mammals, sexual selection
Pubmed
Web of science
Création de la notice
02/11/2017 15:42
Dernière modification de la notice
30/07/2018 17:29
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