Analysis of two cDNA clones encoding the B lymphocyte antigen CD20 (B1, Bp35), a type III integral membrane protein.
Details
Serval ID
serval:BIB_2E22C5000DB8
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Analysis of two cDNA clones encoding the B lymphocyte antigen CD20 (B1, Bp35), a type III integral membrane protein.
Journal
Journal of Experimental Medicine
ISSN
0022-1007[print], 0022-1007[linking]
Publication state
Published
Issued date
1988
Volume
167
Number
6
Pages
1975-1980
Language
english
Notes
Publication types: Journal Article
Abstract
Two cDNA clones encoding the pan-B cell CD20 antigen were isolated from a COS cell expression library. The two clones bear identical coding sequences and differ only in the length of the 3' untranslated region. The predicted CD20 sequence is 297 residues long and contains three hydrophobic domains, one of which is long enough to span the membrane twice. COS cells transfected with either CD20 clone express an immunoreactive protein of 33 kD.
Keywords
Amino Acid Sequence, Antigens, Differentiation, B-Lymphocyte/genetics, B-Lymphocytes/physiology, Base Sequence, Cloning, Molecular, DNA/genetics, Humans, Membrane Proteins/genetics, Molecular Sequence Data
Pubmed
Create date
25/08/2010 15:57
Last modification date
20/08/2019 14:12
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