Analysis of two cDNA clones encoding the B lymphocyte antigen CD20 (B1, Bp35), a type III integral membrane protein.
Détails
ID Serval
serval:BIB_2E22C5000DB8
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Analysis of two cDNA clones encoding the B lymphocyte antigen CD20 (B1, Bp35), a type III integral membrane protein.
Périodique
Journal of Experimental Medicine
ISSN
0022-1007[print], 0022-1007[linking]
Statut éditorial
Publié
Date de publication
1988
Volume
167
Numéro
6
Pages
1975-1980
Langue
anglais
Notes
Publication types: Journal Article
Résumé
Two cDNA clones encoding the pan-B cell CD20 antigen were isolated from a COS cell expression library. The two clones bear identical coding sequences and differ only in the length of the 3' untranslated region. The predicted CD20 sequence is 297 residues long and contains three hydrophobic domains, one of which is long enough to span the membrane twice. COS cells transfected with either CD20 clone express an immunoreactive protein of 33 kD.
Mots-clé
Amino Acid Sequence, Antigens, Differentiation, B-Lymphocyte/genetics, B-Lymphocytes/physiology, Base Sequence, Cloning, Molecular, DNA/genetics, Humans, Membrane Proteins/genetics, Molecular Sequence Data
Pubmed
Création de la notice
25/08/2010 14:57
Dernière modification de la notice
20/08/2019 13:12
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