Clinical value of ambulatory blood pressure monitoring in the assessment of antihypertensive therapy.

Details

Serval ID
serval:BIB_12711
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Clinical value of ambulatory blood pressure monitoring in the assessment of antihypertensive therapy.
Journal
Blood Pressure Monitoring
Author(s)
Waeber B., Brunner H.R.
ISSN
1359-5237
Publication state
Published
Issued date
1999
Peer-reviewed
Oui
Volume
4
Number
5
Pages
263-266
Language
english
Notes
Publication types: Journal Article ; Review
Abstract
Non-invasive ambulatory blood pressure monitoring (ABPM) is particularly useful for assessing the efficacy of antihypertensive drugs. It provides a large number of blood pressure readings during daytime as well as night-time, which results in a more precise assessment of prevailing blood pressure than can be obtained from sporadic measurements taken by a doctor. Because of this greater precision ABPM reduces the number of patients required in clinical trials to demonstrate differences. It also allows one to define precisely the profile of the blood-pressure-lowering effect of a given drug. Placebo has little effect on ABPM. Thus, a placebo phase is not absolutely necessary. ABPM makes it possible to evaluate the efficacy of an antihypertensive medication by analysing data for patients with a placebo effect separately from data for true responders to the medication. In everyday practice ABPM helps one to detect among patients with hypertension refractory to treatment those who exhibit controlled blood pressures outside the medical environment, thus permitting one to avoid an unnecessary step-up of treatment. In addition ABPM can also help one to identify symptoms occurring during antihypertensive treatment that are related to excessive drug-induced changes in blood pressure.
Keywords
Antihypertensive Agents, Blood Pressure Monitoring, Ambulatory, Humans, Hypertension, Placebo Effect, Reproducibility of Results
Pubmed
Create date
19/11/2007 12:04
Last modification date
20/08/2019 12:40
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