Clinical value of ambulatory blood pressure monitoring in the assessment of antihypertensive therapy.

Détails

ID Serval
serval:BIB_12711
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Clinical value of ambulatory blood pressure monitoring in the assessment of antihypertensive therapy.
Périodique
Blood Pressure Monitoring
Auteur⸱e⸱s
Waeber B., Brunner H.R.
ISSN
1359-5237
Statut éditorial
Publié
Date de publication
1999
Peer-reviewed
Oui
Volume
4
Numéro
5
Pages
263-266
Langue
anglais
Notes
Publication types: Journal Article ; Review
Résumé
Non-invasive ambulatory blood pressure monitoring (ABPM) is particularly useful for assessing the efficacy of antihypertensive drugs. It provides a large number of blood pressure readings during daytime as well as night-time, which results in a more precise assessment of prevailing blood pressure than can be obtained from sporadic measurements taken by a doctor. Because of this greater precision ABPM reduces the number of patients required in clinical trials to demonstrate differences. It also allows one to define precisely the profile of the blood-pressure-lowering effect of a given drug. Placebo has little effect on ABPM. Thus, a placebo phase is not absolutely necessary. ABPM makes it possible to evaluate the efficacy of an antihypertensive medication by analysing data for patients with a placebo effect separately from data for true responders to the medication. In everyday practice ABPM helps one to detect among patients with hypertension refractory to treatment those who exhibit controlled blood pressures outside the medical environment, thus permitting one to avoid an unnecessary step-up of treatment. In addition ABPM can also help one to identify symptoms occurring during antihypertensive treatment that are related to excessive drug-induced changes in blood pressure.
Mots-clé
Antihypertensive Agents, Blood Pressure Monitoring, Ambulatory, Humans, Hypertension, Placebo Effect, Reproducibility of Results
Pubmed
Création de la notice
19/11/2007 12:04
Dernière modification de la notice
20/08/2019 12:40
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