Article: article from journal or magazin.
Case report (case report): feedback on an observation with a short commentary.
Gas chromatographic identification and quantification of hydroxyzine: application in a fatal self-poisoning.
Forensic Science International
A method for the identification and quantification of hydroxyzine in human fluids by GC/NPD is presented. The method employs acepromazine as the internal standard and requires no derivatization. After a single alkaline extraction in n-heptane isoamylalcohol (98.5:1.5, v/v), analysis is achieved in 7 min. The lower limit of detectability was 0.8 ng/ml in plasma. Capillary gas chromatography mass spectrometry assay was developed for confirmation. Toxicological findings, after a fatality involving hydroxyzine are presented as an application of the procedure.
Adolescent, Chromatography, Gas, Female, Gas Chromatography-Mass Spectrometry, Humans, Hydroxyzine/analysis, Hydroxyzine/blood, Reproducibility of Results, Suicide
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