Le syndrome antisynthétase: un sous-groupe particulier des myopathies idiopathiques inflammatoires. A propos de trois observations. [Anti-synthetase syndrome: a special subgroup of idiopathic inflammatory myopathies. Apropos of 3 case reports]
Details
Serval ID
serval:BIB_088715A9351B
Type
Article: article from journal or magazin.
Publication sub-type
Case report (case report): feedback on an observation with a short commentary.
Collection
Publications
Institution
Title
Le syndrome antisynthétase: un sous-groupe particulier des myopathies idiopathiques inflammatoires. A propos de trois observations. [Anti-synthetase syndrome: a special subgroup of idiopathic inflammatory myopathies. Apropos of 3 case reports]
Journal
Schweizerische Rundschau fur Medizin Praxis
ISSN
1013-2058 (Print)
Publication state
Published
Issued date
04/1996
Volume
85
Number
16
Pages
508-12
Notes
Case Reports English Abstract Journal Article --- Old month value: Apr 16
Abstract
Anti-synthetase antibodies are found in 20 to 25% of all idiopathic inflammatory myopathies and allow identification of a syndrome associating myositis with interstitial pulmonary disease (50 to 70%), polyarthritis, Raynaud's phenomenon and mechanic's hands. Anti-Jo-1 is the most common anti-synthetase antibody. If anti-Jo-1 is present, interstitial lung disease must be looked for, because this is the most important determinant of the outcome. Treatment with high doses of corticosteroids is required. Immunosuppressive drugs are added in resistant cases or as corticosteroid-sparing agents.
Keywords
Adult Antibodies, Antinuclear/isolation & purification Cough/etiology Dyspnea/etiology Female Humans Ligases/*antagonists & inhibitors/immunology Male Middle Aged Muscle Weakness/*etiology Polymyositis/*etiology/immunology
Pubmed
Create date
25/01/2008 9:39
Last modification date
20/08/2019 13:30
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