Le syndrome antisynthétase: un sous-groupe particulier des myopathies idiopathiques inflammatoires. A propos de trois observations. [Anti-synthetase syndrome: a special subgroup of idiopathic inflammatory myopathies. Apropos of 3 case reports]
Détails
ID Serval
serval:BIB_088715A9351B
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Etude de cas (case report): rapporte une observation et la commente brièvement.
Collection
Publications
Institution
Titre
Le syndrome antisynthétase: un sous-groupe particulier des myopathies idiopathiques inflammatoires. A propos de trois observations. [Anti-synthetase syndrome: a special subgroup of idiopathic inflammatory myopathies. Apropos of 3 case reports]
Périodique
Schweizerische Rundschau fur Medizin Praxis
ISSN
1013-2058 (Print)
Statut éditorial
Publié
Date de publication
04/1996
Volume
85
Numéro
16
Pages
508-12
Notes
Case Reports English Abstract Journal Article --- Old month value: Apr 16
Résumé
Anti-synthetase antibodies are found in 20 to 25% of all idiopathic inflammatory myopathies and allow identification of a syndrome associating myositis with interstitial pulmonary disease (50 to 70%), polyarthritis, Raynaud's phenomenon and mechanic's hands. Anti-Jo-1 is the most common anti-synthetase antibody. If anti-Jo-1 is present, interstitial lung disease must be looked for, because this is the most important determinant of the outcome. Treatment with high doses of corticosteroids is required. Immunosuppressive drugs are added in resistant cases or as corticosteroid-sparing agents.
Mots-clé
Adult Antibodies, Antinuclear/isolation & purification Cough/etiology Dyspnea/etiology Female Humans Ligases/*antagonists & inhibitors/immunology Male Middle Aged Muscle Weakness/*etiology Polymyositis/*etiology/immunology
Pubmed
Création de la notice
25/01/2008 8:39
Dernière modification de la notice
20/08/2019 12:30
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