Article: article from journal or magazin.
Épidermolyse nécrosante suraiguë de Lyell ou toxic epidermal necrolysis. [Toxic epidermal necrolysis]
Revue Médicale Suisse
English Abstract Journal Article --- Old month value: May 2
The toxic epidermal necrolysis (TEN) is an immunologic reaction in the skin with apoptosis of keratinocytes: most cases are reactions against drugs. The main features of this reaction are a separation of the epidermis and erosions of the mucus membranes, associated with a reduction of the general condition with kidney and liver failure. This leads to problems similar to those observed in severely burned patients. The mortality high of patients with TEN can be reduced, if the responsible drug is immediately withdrawn and if the patient is treated in a specialized burns intensive care unit. The medical treatment to stop the chain reaction of apoptosis is still under discussion. Through a case report, this article will focus on the complexity of the treatment of patients with TEN and will point out the importance of a multidisciplinary approach.
Diagnosis, Differential Epidermal Necrolysis, Toxic/classification/*diagnosis/*therapy Humans Male Middle Aged
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