Épidermolyse nécrosante suraiguë de Lyell ou toxic epidermal necrolysis. [Toxic epidermal necrolysis]

Détails

ID Serval
serval:BIB_073D8BBA0929
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Épidermolyse nécrosante suraiguë de Lyell ou toxic epidermal necrolysis. [Toxic epidermal necrolysis]
Périodique
Revue Médicale Suisse
Auteur⸱e⸱s
Bigliardi  P. L., Raffoul  W., Berger  M. M.
ISSN
1660-9379
Statut éditorial
Publié
Date de publication
05/2007
Volume
3
Numéro
109
Pages
1112-4, 1116-8
Notes
English Abstract Journal Article --- Old month value: May 2
Résumé
The toxic epidermal necrolysis (TEN) is an immunologic reaction in the skin with apoptosis of keratinocytes: most cases are reactions against drugs. The main features of this reaction are a separation of the epidermis and erosions of the mucus membranes, associated with a reduction of the general condition with kidney and liver failure. This leads to problems similar to those observed in severely burned patients. The mortality high of patients with TEN can be reduced, if the responsible drug is immediately withdrawn and if the patient is treated in a specialized burns intensive care unit. The medical treatment to stop the chain reaction of apoptosis is still under discussion. Through a case report, this article will focus on the complexity of the treatment of patients with TEN and will point out the importance of a multidisciplinary approach.
Mots-clé
Diagnosis, Differential Epidermal Necrolysis, Toxic/classification/*diagnosis/*therapy Humans Male Middle Aged
Pubmed
Création de la notice
21/01/2008 17:30
Dernière modification de la notice
20/08/2019 12:29
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