Roles of superantigens in microbial infections?

Détails

ID Serval
serval:BIB_CAD8C9943F0D
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Roles of superantigens in microbial infections?
Périodique
Research in Immunology
Auteur⸱e⸱s
Acha-Orbea H.
ISSN
0923-2494 (Print)
ISSN-L
0923-2494
Statut éditorial
Publié
Date de publication
1993
Volume
144
Numéro
3
Pages
198-201; discussion 214-22
Langue
anglais
Résumé
Superantigens have been defined in a variety of infectious particles such as bacteria and viruses. These superantigens have the capacity to stimulate a large percentage of the host T cells by interacting specifically with the T-cell receptor V beta chain which is shared by about 1-20% of mature T cells. The recent discovery that mammary tumour viruses express such superantigens enabled the analysis of the retroviral life cycle and led to questions about the role of superantigen in amplification of the infection.
Mots-clé
Animals, Bacterial Infections/immunology, Lymphocyte Activation, Mice, Minor Lymphocyte Stimulatory Antigens/immunology, Receptors, Antigen, T-Cell, alpha-beta/immunology, Superantigens/immunology, T-Lymphocytes/immunology, Virus Diseases/immunology
Pubmed
Web of science
Création de la notice
24/01/2008 14:47
Dernière modification de la notice
20/08/2019 15:45
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