PPAR gamma: ally and foe in bone metabolism.
Détails
ID Serval
serval:BIB_8FFE2B0EC4D7
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Lettre (letter): communication adressée à l'éditeur.
Collection
Publications
Institution
Titre
PPAR gamma: ally and foe in bone metabolism.
Périodique
Cell Metabolism
ISSN
1550-4131[print]
Statut éditorial
Publié
Date de publication
2008
Volume
7
Numéro
3
Pages
188-190
Langue
anglais
Résumé
Bone homeostasis is a well-balanced process that is largely dependent on the contribution of both bone-forming osteoblasts and bone-resorbing osteoclasts. A new study (Wan et al., 2007) suggests a previously unsuspected role for the transcription factor PPARgamma in promoting bone progenitors to the osteoclastic lineage.
Mots-clé
Animals, Bone Remodeling/drug effects, Bone Resorption/metabolism, Cell Differentiation, Cell Lineage, Hematopoietic Stem Cells/metabolism, Humans, Mice, Mice, Knockout, NF-kappa B/metabolism, Osteoblasts/drug effects, Osteoblasts/metabolism, Osteoclasts/drug effects, Osteoclasts/metabolism, Osteopetrosis/metabolism, PPAR gamma/agonists, PPAR gamma/genetics, Proto-Oncogene Proteins c-fos/metabolism, Signal Transduction/drug effects, Thiazolidinediones/pharmacology
Pubmed
Web of science
Open Access
Oui
Création de la notice
29/01/2009 22:14
Dernière modification de la notice
20/08/2019 14:53
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