La rate: entre mystères et découvertes [The spleen: between mysteries and discoveries].

Détails

ID Serval
serval:BIB_82B7AC9B61E9
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
La rate: entre mystères et découvertes [The spleen: between mysteries and discoveries].
Périodique
Revue Médicale Suisse
Auteur(s)
Leuenberger M., Sartori C.
ISSN
1660-9379[print], 1660-9379[linking]
Statut éditorial
Publié
Date de publication
2010
Volume
6
Numéro
269
Pages
2080-2085
Langue
français
Notes
Publication types: English Abstract ; Journal ArticlePublication Status: ppublish
Résumé
Mainly because it is possible to live without it, the spleen has always been considered a secondary and mysterious organ. However, recent observations have revealed new unsuspected functions for this organ whose patho-physiological importance should be reconsidered. Much less known than the hypersplenism, the hyposplenism corresponds historically to the loss or the insufficiency of the two principal functions of spleen: the filtration of faded or senescent elements from the blood and the fight against infections. In this article, after a short recall of the physiological functions of spleen, three innovations relating to hyposplenism will be explored: the vascular complications, the loss of the splenic pool of regenerating monocytes and the loss of the splenic pool of pluripotent mesenchymal stem cell.
Mots-clé
Algorithms, Atherosclerosis/physiopathology, Humans, Mesenchymal Stem Cells, Monocytes/metabolism, Phagocytosis, Risk Factors, Spleen/blood supply, Spleen/physiology, Splenic Diseases/blood, Splenic Diseases/complications, Thromboembolism/physiopathology
Pubmed
Création de la notice
18/03/2011 10:51
Dernière modification de la notice
20/08/2019 15:42
Données d'usage