The FASTK family of proteins: emerging regulators of mitochondrial RNA biology.

Détails

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Etat: Public
Version: Final published version
Licence: CC BY-NC 4.0
ID Serval
serval:BIB_3F87E3AD1020
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
The FASTK family of proteins: emerging regulators of mitochondrial RNA biology.
Périodique
Nucleic acids research
Auteur⸱e⸱s
Jourdain A.A., Popow J., de la Fuente M.A., Martinou J.C., Anderson P., Simarro M.
ISSN
1362-4962 (Electronic)
ISSN-L
0305-1048
Statut éditorial
Publié
Date de publication
02/11/2017
Peer-reviewed
Oui
Volume
45
Numéro
19
Pages
10941-10947
Langue
anglais
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Résumé
The FASTK family proteins have recently emerged as key post-transcriptional regulators of mitochondrial gene expression. FASTK, the founding member and its homologs FASTKD1-5 are architecturally related RNA-binding proteins, each having a different function in the regulation of mitochondrial RNA biology, from mRNA processing and maturation to ribosome assembly and translation. In this review, we outline the structure, evolution and function of these FASTK proteins and discuss the individual role that each has in mitochondrial RNA biology. In addition, we highlight the aspects of FASTK research that still require more attention.
Mots-clé
Gene Expression Regulation, Humans, Mitochondrial Proteins/genetics, Mitochondrial Proteins/metabolism, Protein Serine-Threonine Kinases/genetics, Protein Serine-Threonine Kinases/metabolism, RNA/genetics, RNA/metabolism, RNA, Messenger/genetics, RNA, Messenger/metabolism, RNA, Mitochondrial, RNA-Binding Proteins/genetics, RNA-Binding Proteins/metabolism
Pubmed
Web of science
Open Access
Oui
Création de la notice
13/04/2021 17:25
Dernière modification de la notice
08/02/2022 7:36
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