The FASTK family of proteins: emerging regulators of mitochondrial RNA biology.

Details

Serval ID
serval:BIB_3F87E3AD1020
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
The FASTK family of proteins: emerging regulators of mitochondrial RNA biology.
Journal
Nucleic acids research
Author(s)
Jourdain Alexis
Publication state
Published
Issued date
01/11/2017
Language
english
Abstract
The FASTK family proteins have recently emerged as key post-transcriptional regulators of mitochondrial gene expression. FASTK, the founding member and its homologs FASTKD1-5 are architecturally related RNA-binding proteins, each having a different function in the regulation of mitochondrial RNA biology, from mRNA processing and maturation to ribosome assembly and translation. In this review, we outline the structure, evolution and function of these FASTK proteins and discuss the individual role that each has in mitochondrial RNA biology. In addition, we highlight the aspects of FASTK research that still require more attention.
Pubmed
Create date
13/04/2021 17:25
Last modification date
14/04/2021 6:37
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