A probabilistic approach to evaluate salivary microbiome in forensic science when the Defense says: `It is my twin brother'.

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Version: Author's accepted manuscript
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Serval ID
serval:BIB_4128349F27C6
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
A probabilistic approach to evaluate salivary microbiome in forensic science when the Defense says: `It is my twin brother'.
Journal
Forensic science international. Genetics
Author(s)
Bozza S., Scherz V., Greub G., Falquet L., Taroni F.
ISSN
1878-0326 (Electronic)
ISSN-L
1872-4973
Publication state
Published
Issued date
03/2022
Peer-reviewed
Oui
Volume
57
Pages
102638
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Abstract
Salivary microbiota profiles may represent a valid contribution to forensic investigation when standard DNA genotyping methods fail. Starting from questioned and control materials in the form of saliva, the evidence can be expressed by means of a distance between those materials taking into account specific aspects of the microbiota composition. The value of the evidence for forensic discrimination purposes is quantified by means of a Bayes' factor, that allows one to overcome the major limitations and pitfalls of intuition connected to the use of cut-off values as a mean of decision.
Keywords
Bayes Theorem, Forensic Medicine, Humans, Male, Microbiota/genetics, Saliva, Siblings, Bayes’ factor, Cut-off, Discrimination, Evaluation of evidence, Monozygotic twins, Salivary microbiome, Similarity score
Pubmed
Web of science
Funding(s)
Swiss National Science Foundation
Create date
08/12/2021 14:29
Last modification date
03/08/2022 7:09
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