Ionotropic receptors (IRs): chemosensory ionotropic glutamate receptors in Drosophila and beyond.

Détails

Ressource 1Télécharger: BIB_FE442C4FF36A.P001.pdf (1642.74 [Ko])
Etat: Public
Version: Final published version
ID Serval
serval:BIB_FE442C4FF36A
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
Ionotropic receptors (IRs): chemosensory ionotropic glutamate receptors in Drosophila and beyond.
Périodique
Insect Biochemistry and Molecular Biology
Auteur(s)
Rytz R., Croset V., Benton R.
ISSN
1879-0240 (Electronic)
ISSN-L
0965-1748
Statut éditorial
Publié
Date de publication
2013
Peer-reviewed
Oui
Volume
43
Numéro
9
Pages
888-897
Langue
anglais
Résumé
Ionotropic Receptors (IRs) are a recently characterized family of olfactory receptors in the fruit fly, Drosophila melanogaster. IRs are not related to insect Odorant Receptors (ORs), but rather have evolved from ionotropic glutamate receptors (iGluRs), a conserved family of synaptic ligand-gated ion channels. Here, we review the expression and function of IRs in Drosophila, highlighting similarities and differences with iGluRs. We also briefly describe the organization of the neuronal circuits in which IRs function, comparing and contrasting them with the sensory pathways expressing ORs. Finally, we summarize the bioinformatic identification and initial characterization of IRs in other species, which imply an evolutionarily conserved role for these receptors in chemosensation in insects and other protostomes.
Pubmed
Web of science
Open Access
Oui
Création de la notice
17/04/2013 16:56
Dernière modification de la notice
20/08/2019 16:28
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