Design and methodology of the Swiss Transplant Cohort Study (STCS): a comprehensive prospective nationwide long-term follow-up cohort.

Détails

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Etat: Public
Version: de l'auteur
ID Serval
serval:BIB_FD731E51329C
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Design and methodology of the Swiss Transplant Cohort Study (STCS): a comprehensive prospective nationwide long-term follow-up cohort.
Périodique
European Journal of Epidemiology
Auteur(s)
Koller M.T., van Delden C., Müller N.J., Baumann P., Lovis C., Marti H.P., Fehr T., Binet I., De Geest S., Bucher H.C., Meylan P., Pascual M., Steiger J.
ISSN
1573-7284 (Electronic)
ISSN-L
0393-2990
Statut éditorial
Publié
Date de publication
2013
Volume
28
Numéro
4
Pages
347-355
Langue
anglais
Notes
Publication types: Journal ArticlePublication Status: ppublish
Résumé
In Switzerland, organ procurement is well organized at the national-level but transplant outcomes have not been systematically monitored so far. Therefore, a novel project, the Swiss Transplant Cohort Study (STCS), was established. The STCS is a prospective multicentre study, designed as a dynamic cohort, which enrolls all solid organ recipients at the national level. The features of the STCS are a flexible patient-case system that allows capturing all transplant scenarios and collection of patient-specific and allograft-specific data. Beyond comprehensive clinical data, specific focus is directed at psychosocial and behavioral factors, infectious disease development, and bio-banking. Between May 2008 and end of 2011, the six Swiss transplant centers recruited 1,677 patients involving 1,721 transplantations, and a total of 1,800 organs implanted in 15 different transplantation scenarios. 10 % of all patients underwent re-transplantation and 3% had a second transplantation, either in the past or during follow-up. 34% of all kidney allografts originated from living donation. Until the end of 2011 we observed 4,385 infection episodes in our patient population. The STCS showed operative capabilities to collect high-quality data and to adequately reflect the complexity of the post-transplantation process. The STCS represents a promising novel project for comparative effectiveness research in transplantation medicine.
Pubmed
Web of science
Open Access
Oui
Création de la notice
20/06/2013 17:04
Dernière modification de la notice
20/08/2019 16:28
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