Somatic growth in children with congenital heart disease at 10 years of age: Risk factors and longitudinal growth.
Details
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State: Public
Version: Final published version
License: CC BY-NC-ND 4.0
State: Public
Version: Final published version
License: CC BY-NC-ND 4.0
Serval ID
serval:BIB_FD0E55A19547
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Somatic growth in children with congenital heart disease at 10 years of age: Risk factors and longitudinal growth.
Journal
Early human development
ISSN
1872-6232 (Electronic)
ISSN-L
0378-3782
Publication state
Published
Issued date
05/2021
Peer-reviewed
Oui
Volume
156
Pages
105349
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Publication Status: ppublish
Abstract
Children with congenital heart disease (CHD) are at risk of impaired growth.
To describe height, weight, head circumference (HC), and body mass index (BMI) at 10 years and identify risk factors for altered longitudinal growth in children with CHD.
Growth parameters were evaluated from birth until 10 years using z-scores. The impact of cardiac and noncardiac factors on longitudinal growth was investigated.
A total of 135 children with different types of CHD who underwent cardiopulmonary bypass surgery, no genetic disorder.
Head circumference, weight, height and BMI.
At 10 years, z-scores for height and BMI did not differ from the Swiss population (P > 0.1). Z-scores for weight and HC were significantly below the norm (-0.38 and - 0.71, P < 0.01). From 1 to 10 years, all growth parameters except BMI increased significantly (P ≤ 0.001, BMI: P = 0.14). Lower gestational age and longer length of hospitalization were associated with either impaired head circumference or length at 10 years, while lower socioeconomic status was associated with higher BMI and weight at 10 years (all P < 0.05).
Despite partial catch-up, somatic growth remains impaired in children with CHD with weight and HC below the norm at 10 years. The only cardiac factor associated with impaired longitudinal growth was duration of hospital stay. Furthermore, lower socioeconomic background may pose a risk of overweight at older age. Close monitoring of growth parameters and parental counselling in all CHD children is advisable beyond early childhood to ensure optimal somatic growth.
To describe height, weight, head circumference (HC), and body mass index (BMI) at 10 years and identify risk factors for altered longitudinal growth in children with CHD.
Growth parameters were evaluated from birth until 10 years using z-scores. The impact of cardiac and noncardiac factors on longitudinal growth was investigated.
A total of 135 children with different types of CHD who underwent cardiopulmonary bypass surgery, no genetic disorder.
Head circumference, weight, height and BMI.
At 10 years, z-scores for height and BMI did not differ from the Swiss population (P > 0.1). Z-scores for weight and HC were significantly below the norm (-0.38 and - 0.71, P < 0.01). From 1 to 10 years, all growth parameters except BMI increased significantly (P ≤ 0.001, BMI: P = 0.14). Lower gestational age and longer length of hospitalization were associated with either impaired head circumference or length at 10 years, while lower socioeconomic status was associated with higher BMI and weight at 10 years (all P < 0.05).
Despite partial catch-up, somatic growth remains impaired in children with CHD with weight and HC below the norm at 10 years. The only cardiac factor associated with impaired longitudinal growth was duration of hospital stay. Furthermore, lower socioeconomic background may pose a risk of overweight at older age. Close monitoring of growth parameters and parental counselling in all CHD children is advisable beyond early childhood to ensure optimal somatic growth.
Keywords
Aged, Body Height, Body Mass Index, Body Weight, Cephalometry, Child, Child, Preschool, Heart Defects, Congenital/epidemiology, Humans, Prospective Studies, Risk Factors, Body mass index, Congenital heart disease, Longitudinal growth, Risk factors, School-age, Somatic growth
Pubmed
Web of science
Open Access
Yes
Create date
24/04/2021 14:58
Last modification date
12/10/2023 6:18