Blood pressure monitoring for quality assessment of antihypertensive therapy

Details

Serval ID
serval:BIB_FC55B7F18622
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Blood pressure monitoring for quality assessment of antihypertensive therapy
Journal
Journal of Cardiovascular Pharmacology
Author(s)
Brunner  H. R., Waeber  B., Nussberger  J.
ISSN
0160-2446 (Print)
Publication state
Published
Issued date
1986
Volume
8 Suppl 6
Pages
S55-9
Notes
Journal Article
Abstract
Despite many new therapeutic approaches to the treatment of hypertension and new diagnostic methods, the measurement of the most basic parameter, the blood pressure itself, has not changed over many years. The most commonly used method records the blood pressure on a single occasion and it is then assumed that this single reading is representative of the blood pressure of that patient at all times. This paper presents evidence, based on published studies, showing that the single "office" blood pressure reading gives little information about the blood pressure during daily activities. A study in 101 volunteers and a study in 38 patients with hypertension both showed that, not only is the "office" reading not the same as the average of many blood pressure readings made over 24 h using a Remler device, but also that the difference cannot be predicted. In some cases, the "office" pressure is higher and in some cases lower than the Remler blood pressure. This difference may explain the apparent blood pressure lowering effect of placebo. This has been frequently reported when the blood pressure is measured by the physician but ambulatory blood pressure readings have failed to show this effect. Finally, the inaccuracy of the "office" blood pressure may obscure smaller differences between two treatment groups in a clinical trial which could have been clearly demonstrated if the blood pressure had been recorded using an ambulatory method.
Keywords
Ambulatory Care Antihypertensive Agents/*therapeutic use Blood Pressure/*drug effects Forecasting Humans *Monitoring, Physiologic
Pubmed
Web of science
Create date
05/03/2008 16:41
Last modification date
20/08/2019 16:27
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