Meet your MAKR: the membrane-associated kinase regulator protein family in the regulation of plant development.
Details
Serval ID
serval:BIB_FBF41837BC83
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Meet your MAKR: the membrane-associated kinase regulator protein family in the regulation of plant development.
Journal
The FEBS journal
ISSN
1742-4658 (Electronic)
ISSN-L
1742-464X
Publication state
Published
Issued date
10/2022
Peer-reviewed
Oui
Volume
289
Number
20
Pages
6172-6186
Language
english
Notes
Publication types: Journal Article ; Review ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Publication Status: ppublish
Abstract
A small family composed of BRI1 KINASE INHIBITOR1 (BKI1) and MEMBRANE-ASSOCIATED KINASE REGULATORS (MAKRs) has recently captured the attention of plant biologists, due to their involvement in developmental processes downstream of hormones and Receptor-Like Kinases (RLK) signalling. BKI1/MAKRs are intrinsically disordered proteins (so-called unstructured proteins) and as such lack specific domains. Instead, they are defined by the presence of two conserved linear motifs involved in the interaction with lipids and proteins, respectively. Here, we first relate the discovery of the MAKR gene family. Then, we review the individual function of characterized family members and discuss their shared and specific modes of action. Finally, we explore and summarize the structural, comparative and functional genomics data available on this gene family. Together, this review aims at building a comprehensive reference about BKI1/MAKR protein function in plants.
Keywords
Arabidopsis/genetics, Arabidopsis Proteins/metabolism, Brassinosteroids, Gene Expression Regulation, Plant, Hormones/metabolism, Intrinsically Disordered Proteins/metabolism, Membrane Proteins/genetics, Membrane Proteins/metabolism, Plant Development/genetics, Plants/genetics, Plants/metabolism, Protein Kinases/metabolism, Signal Transduction/genetics, auxin, brassinosteroids, lateral root, receptor-like kinase, vascular development
Pubmed
Web of science
Create date
26/07/2021 8:22
Last modification date
05/10/2023 5:59
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