Infection and chronic allograft dysfunction.

Détails

ID Serval
serval:BIB_FB23C165F8B3
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
Infection and chronic allograft dysfunction.
Périodique
Kidney International. Supplement
Auteur(s)
Dupont P.J., Manuel O., Pascual M.
ISSN
0098-6577 (Print)
ISSN-L
0098-6577
Statut éditorial
Publié
Date de publication
2010
Volume
78
Numéro
119
Pages
S47-S53
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't ; Review
Publication Status: ppublish
Résumé
With the advent of more potent immunosuppressive regimens, the incidence of acute rejection following renal transplantation has declined sharply in recent years. In spite of this, long-term graft outcomes remain suboptimal because of relentless attrition by cumulated insults to the allograft. As acute rejection rates have declined, other causes of graft injury and loss have recently emerged. Among these, infectious diseases remain a persistent threat and can be associated with allograft dysfunction. This group includes nephropathy due to polyoma (BK) virus infection, cytomegalovirus disease, and bacterial infection (the latter most commonly arising from the urinary tract). Rarer infectious causes of chronic allograft dysfunction include cryoglobulinemia associated with hepatitis C, Epstein-Barr virus-associated posttransplant lymphoproliferative disease, and direct cytotoxicity from adenoviral infection or parvovirus B19.
Mots-clé
Animals, Chronic Disease, Communicable Diseases/etiology, Communicable Diseases/microbiology, Graft Rejection/etiology, Graft Rejection/microbiology, Humans, Immunosuppressive Agents/adverse effects, Kidney/microbiology, Kidney/physiopathology, Kidney Diseases/etiology, Kidney Diseases/microbiology, Kidney Transplantation/adverse effects, Risk Assessment, Risk Factors, Transplantation, Homologous, Treatment Outcome
Pubmed
Création de la notice
20/12/2010 11:09
Dernière modification de la notice
03/03/2018 22:57
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