Whose arm is it anyway? An fMRI case study of supernumerary phantom limb.

Details

Serval ID
serval:BIB_F9DDB327E8C1
Type
Article: article from journal or magazin.
Publication sub-type
Case report (case report): feedback on an observation with a short commentary.
Collection
Publications
Title
Whose arm is it anyway? An fMRI case study of supernumerary phantom limb.
Journal
Brain
Author(s)
McGonigle D.J., Hänninen R., Salenius S., Hari R., Frackowiak R.S., Frith C.D.
ISSN
0006-8950 (Print)
ISSN-L
0006-8950
Publication state
Published
Issued date
2002
Volume
125
Number
Pt 6
Pages
1265-1274
Language
english
Notes
Publication types: Case Reports ; Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov'tPublication Status: ppublish
Abstract
Under normal circumstances, information from a number of sources is combined to compute a unitary percept of the body. However, after pathology these influences may be perceived simultaneously, resulting in multiple dissociated conscious representations. In a recent paper, we described subject E.P., a right-handed female stroke patient with a right frontomesial lesion who sporadically experiences a supernumerary 'ghost' left arm that occupies the previous position of the real left arm after a delay of 60-90 s. We used a delayed response paradigm with functional MRI to examine the haemodynamic correlates of E.P.'s illusion. Comparison of periods of time during scanning when the ghost arm was present against when it was not revealed a single cluster (9 voxels, t = 5.11, P < 0.012 corrected for multiple comparisons) located on the right medial wall in the supplementary motor area ('SMA proper'). Our results suggest that areas traditionally classified as part of the motor system can influence the conscious perception of the body. We propose that, as a consequence of her injury, E.P. is aware of the position of the phantom limb in this 'action space' while also continuing to be aware of the true position of her real limb on the basis of afferent somatosensory information.
Keywords
Adult, Arm/physiology, Female, Humans, Magnetic Resonance Imaging/methods, Motor Cortex/physiology, Phantom Limb/diagnosis, Phantom Limb/physiopathology
Pubmed
Web of science
Open Access
Yes
Create date
12/09/2011 18:31
Last modification date
20/08/2019 17:25
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