Paediatric bi-ventricular external assist device based on artificial muscles

Détails

ID Serval
serval:BIB_F99382F6959A
Type
Actes de conférence (partie): contribution originale à la littérature scientifique, publiée à l'occasion de conférences scientifiques, dans un ouvrage de compte-rendu (proceedings), ou dans l'édition spéciale d'un journal reconnu (conference proceedings).
Sous-type
Abstract (résumé de présentation): article court qui reprend les éléments essentiels présentés à l'occasion d'une conférence scientifique dans un poster ou lors d'une intervention orale.
Collection
Publications
Titre
Paediatric bi-ventricular external assist device based on artificial muscles
Titre de la conférence
45th Congress of the European Society for Surgical Research
Auteur(s)
Michalis A., Tozzi P., Burki M., Berdajs D., Taub S., von Segesser L. K.
Adresse
Geneva - Switzerland, 9-12 June, 2010
ISBN
0007-1323
Statut éditorial
Publié
Date de publication
2010
Peer-reviewed
Oui
Volume
97
Série
British Journal of Surgery
Pages
S36-S36
Langue
anglais
Notes
Meeting Abstract
Résumé
Objective:
Existing VADs are single-ventricle pumps needing anticoagulation. We developed a bi ventricular external assist device that reproduces the physiological heart muscle movement completely avoiding anticoagulants.
Methods:
The device has a carbon fibre skeleton fitting a 30-40 kg patient's heart, to which a Nitinol based artificial muscle is connected. The artificial muscle wraps both ventricles. The strength of the Nitinol fibres is amplified by a pivot articulation in contact with the ventricle wall. The fibres are
electrically driven and a dedicated control unit has been developed. We assessed hemodynamic performances of this device using a previously described dedicated bench test. Volume ejected and pressure gradient has been measured with afterload ranging from 25 to 50mmHg.
Results:
With anafterload of 50mmHg the system has an ejection fraction (EF) of 10% on the right side and 8% on the left side. The system is able to generate a systolic ejection of 5,5 ml on the right side and 4,4 ml on the left side. With anafterload of 25mmHg the results are reduced of about 20%. The activation frequency is 80/minute resulting in a total volume displacement of 440 ml/minute on the right side and 352 ml/minute on the left side.
Conclusions:
The artificial muscle follows Starling's law as the ejected volume increases when afterload increases. These preliminary studies confirmed the possibility of improving the EF of a failing heart using artificial muscle for external cardiac compression. This device could be helpful in weaning CPB and/or for short-term cardio-circulatory support in paediatric population with
cardiac failure.
Web of science
Création de la notice
21/10/2010 11:20
Dernière modification de la notice
03/03/2018 22:54
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