The functional anatomy of motor recovery after stroke in humans: a study with positron emission tomography.

Détails

ID Serval
serval:BIB_F851BB2D1FC2
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
The functional anatomy of motor recovery after stroke in humans: a study with positron emission tomography.
Périodique
Annals of Neurology
Auteur(s)
Chollet F., DiPiero V., Wise R.J., Brooks D.J., Dolan R.J., Frackowiak R.S.
ISSN
0364-5134 (Print)
ISSN-L
0364-5134
Statut éditorial
Publié
Date de publication
1991
Volume
29
Numéro
1
Pages
63-71
Langue
anglais
Notes
Publication types: Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov'tPublication Status: ppublish
Résumé
We have studied regional cerebral blood flow changes in 6 patients after their recovery from a first hemiplegic stroke. All had a single well-defined hemispheric lesion and at least a brachial monoparesis that subsequently recovered. Each patient had 6 measurements of cerebral blood flow by positron tomography with 2 scans at rest, 2 during movement of fingers of the recovered hand, and 2 during movement of fingers of the normal hand. When the normal fingers were moved, regional cerebral blood flow increased significantly in contralateral primary sensorimotor cortex and in the ipsilateral cerebellar hemisphere. When the fingers of the recovered hand were moved, significant regional cerebral blood flow increases were observed in both contralateral and ipsilateral primary sensorimotor cortex and in both cerebellar hemispheres. Other regions, namely, insula, inferior parietal, and premotor cortex, were also bilaterally activated with movement of the recovered hand. We have also demonstrated, by using a new technique of image analysis, different functional connections between the thalamic nuclei and specific cortical and cerebellar regions during these movements. Our results suggest that ipsilateral motor pathways may play a role in the recovery of motor function after ischemic stroke.
Mots-clé
Adult, Aged, Cerebellum/physiology, Cerebellum/radionuclide imaging, Cerebrovascular Circulation/physiology, Cerebrovascular Disorders/complications, Cerebrovascular Disorders/physiopathology, Female, Fingers/physiopathology, Hemiplegia/etiology, Hemiplegia/physiopathology, Humans, Male, Middle Aged, Motor Cortex/physiology, Motor Cortex/radionuclide imaging, Movement/physiology, Somatosensory Cortex/physiology, Somatosensory Cortex/radionuclide imaging, Tomography, Emission-Computed
Pubmed
Web of science
Création de la notice
06/10/2011 20:18
Dernière modification de la notice
03/03/2018 22:51
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