Delayed contrast-enhanced MRI of the coronary artery wall in takayasu arteritis.

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Etat: Serval
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ID Serval
serval:BIB_F7EFFFF5B3F2
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Delayed contrast-enhanced MRI of the coronary artery wall in takayasu arteritis.
Périodique
Plos One
Auteur(s)
Schneeweis C., Schnackenburg B., Stuber M., Berger A., Schneider U., Yu J., Gebker R., Weiss R.G., Fleck E., Kelle S.
ISSN
1932-6203 (Electronic)
ISSN-L
1932-6203
Statut éditorial
Publié
Date de publication
2012
Peer-reviewed
Oui
Volume
7
Numéro
12
Pages
e50655
Langue
anglais
Notes
Publication types: Journal Article
Résumé
BACKGROUND: Takayasu arteritis (TA) is a rare form of chronic inflammatory granulomatous arteritis of the aorta and its major branches. Late gadolinium enhancement (LGE) with magnetic resonance imaging (MRI) has demonstrated its value for the detection of vessel wall alterations in TA. The aim of this study was to assess LGE of the coronary artery wall in patients with TA compared to patients with stable CAD.
METHODS: We enrolled 9 patients (8 female, average age 46±13 years) with proven TA. In the CAD group 9 patients participated (8 male, average age 65±10 years). Studies were performed on a commercial 3T whole-body MR imaging system (Achieva; Philips, Best, The Netherlands) using a 3D inversion prepared navigator gated spoiled gradient-echo sequence, which was repeated 34-45 minutes after low-dose gadolinium administration.
RESULTS: No coronary vessel wall enhancement was observed prior to contrast in either group. Post contrast, coronary LGE on IR scans was detected in 28 of 50 segments (56%) seen on T2-Prep scans in TA and in 25 of 57 segments (44%) in CAD patients. LGE quantitative assessment of coronary artery vessel wall CNR post contrast revealed no significant differences between the two groups (CNR in TA: 6.0±2.4 and 7.3±2.5 in CAD; p = 0.474).
CONCLUSION: Our findings suggest that LGE of the coronary artery wall seems to be common in patients with TA and similarly pronounced as in CAD patients. The observed coronary LGE seems to be rather unspecific, and differentiation between coronary vessel wall fibrosis and inflammation still remains unclear.
Pubmed
Web of science
Open Access
Oui
Création de la notice
10/01/2013 19:08
Dernière modification de la notice
09/05/2019 3:40
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