Percutaneous vertebroplasty for pain management in malignant fractures of the spine with epidural involvement.

Détails

ID Serval
serval:BIB_F7E2A08BBBF4
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Percutaneous vertebroplasty for pain management in malignant fractures of the spine with epidural involvement.
Périodique
Radiology
Auteur(s)
Saliou G., Kocheida el M, Lehmann P., Depriester C., Paradot G., Le Gars D., Balut A., Deramond H.
ISSN
1527-1315 (Electronic)
ISSN-L
0033-8419
Statut éditorial
Publié
Date de publication
03/2010
Peer-reviewed
Oui
Volume
254
Numéro
3
Pages
882-890
Langue
anglais
Notes
Saliou, Guillaume
Kocheida, El Moncef
Lehmann, Pierre
Depriester, Claude
Paradot, Gaelle
Le Gars, Daniel
Balut, Antonia
Deramond, Herve
eng
2010/02/24 06:00
Radiology. 2010 Mar;254(3):882-90. doi: 10.1148/radiol.09081698.
Publication types: Journal Article
Publication Status: ppublish
Résumé
To evaluate the feasibility, efficacy, and safety of percutaneous vertebroplasty (PV) in the treatment of pathologic fractures owing to malignancy with epidural involvement, with or without neurologic symptoms of spinal cord or cauda equina compression.
This study was approved by the local ethics committee; informed consent was obtained from all patients. This retrospective review was performed for 51 consecutive patients with metastatic disease or multiple myeloma treated by means of vertebroplasty, who presented with at least one vertebral lesion with epidural involvement, with or without clinical symptoms of spinal cord or cauda equina compression. All patients with neurologic deficit were terminally ill. A neurologic examination was performed before and after treatment in all patients. All imaging examinations and treatments were reviewed, and chi(2), Mann Whitney, or Fisher exact testing was performed for univariate analysis of variables.
A total of 74 vertebrae were treated in 51 patients, 22 women and 29 men with a mean age of 62.5 years (range, 28-85 years). Fifteen (29%) patients presented symptoms of complete or incomplete spinal cord or cauda equina compression before vertebroplasty and no further clinical deterioration was observed after treatment. The analgesic efficacy of vertebroplasty was satisfactory for 94% (48 of 51) of patients after 1 day, 86% (31 of 36) patients after 1 month, and 92% (11 of 12) patients after 1 year. One patient with no clinical neurologic deficit before treatment experienced symptoms of cauda equina compression 2 days after vertebroplasty. No other major complication was observed.
The feasibility, efficacy, and safety of PV were confirmed in patients experiencing pain related to malignant spinal tumors with epidural extension, with a low complication rate. PV should become part of the palliative analgesic treatment for such patients. (c) RSNA, 2010.

Mots-clé
Adult, Aged, Aged, 80 and over, Bone Cements, Chi-Square Distribution, Feasibility Studies, Female, Humans, Male, Middle Aged, Neoplasm Invasiveness, Pain/etiology, Pain/surgery, Pain Measurement, Retrospective Studies, Spinal Fractures/diagnostic imaging, Spinal Fractures/etiology, Spinal Fractures/pathology, Spinal Fractures/surgery, Spinal Neoplasms/complications, Spinal Neoplasms/diagnostic imaging, Spinal Neoplasms/pathology, Spinal Neoplasms/surgery, Statistics, Nonparametric, Tomography, X-Ray Computed, Treatment Outcome, Vertebroplasty/methods
Pubmed
Création de la notice
20/01/2017 16:30
Dernière modification de la notice
03/03/2018 22:51
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