Article: article from journal or magazin.
Serum hyperglycosylated human chorionic gonadotropin to predict the gestational outcome in in vitro fertilization/intracytoplasmic sperm injection pregnancies.
Fetal Diagnosis and Therapy
Publication types: Evaluation Studies ; Journal Article
Hyperglycosylated human chorionic gonadotropin (H-hCG) is secreted by the placenta in early pregnancy. Decreased H-hCG levels have been associated with abortion in spontaneous pregnancy. We retrospectively measured H-hCG and dimeric hCG in the sera of 87 in vitro fertilization patients obtained in the 3 weeks following embryo transfer and set the results in relation to pregnancy outcome. H-hCG and dimeric hCG were correlated (r(2) = 0.89), and were significantly decreased in biochemical pregnancy (2 microg/l and 18 IU/l, respectively) compared to early pregnancy loss (22 microg/l and 331 IU/l) and ongoing pregnancy (32 microg/l and 353 IU/l). Only H-hCG tended to discriminate between these last two groups.
Chorionic Gonadotropin, Female, Fertilization in Vitro, Glycosylation, Humans, Pregnancy, Pregnancy Outcome, Pregnancy Tests, Retrospective Studies, Sperm Injections, Intracytoplasmic
Web of science
Last modification date