Serum hyperglycosylated human chorionic gonadotropin to predict the gestational outcome in in vitro fertilization/intracytoplasmic sperm injection pregnancies.

Détails

ID Serval
serval:BIB_F7D6605B13C1
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Serum hyperglycosylated human chorionic gonadotropin to predict the gestational outcome in in vitro fertilization/intracytoplasmic sperm injection pregnancies.
Périodique
Fetal Diagnosis and Therapy
Auteur(s)
Bersinger N.A., Wunder D.M., Nicolas M., Birkhäuser M.H., Porquet D., Guibourdenche J.
ISSN
1421-9964
Statut éditorial
Publié
Date de publication
2008
Peer-reviewed
Oui
Volume
24
Numéro
1
Pages
74-78
Langue
anglais
Notes
Publication types: Evaluation Studies ; Journal Article
Résumé
Hyperglycosylated human chorionic gonadotropin (H-hCG) is secreted by the placenta in early pregnancy. Decreased H-hCG levels have been associated with abortion in spontaneous pregnancy. We retrospectively measured H-hCG and dimeric hCG in the sera of 87 in vitro fertilization patients obtained in the 3 weeks following embryo transfer and set the results in relation to pregnancy outcome. H-hCG and dimeric hCG were correlated (r(2) = 0.89), and were significantly decreased in biochemical pregnancy (2 microg/l and 18 IU/l, respectively) compared to early pregnancy loss (22 microg/l and 331 IU/l) and ongoing pregnancy (32 microg/l and 353 IU/l). Only H-hCG tended to discriminate between these last two groups.
Mots-clé
Chorionic Gonadotropin, Female, Fertilization in Vitro, Glycosylation, Humans, Pregnancy, Pregnancy Outcome, Pregnancy Tests, Retrospective Studies, Sperm Injections, Intracytoplasmic
Pubmed
Web of science
Création de la notice
04/03/2009 20:09
Dernière modification de la notice
03/03/2018 22:50
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