Radiological profile of anemia on unenhanced MDCT of the thorax.

Détails

ID Serval
serval:BIB_F7A2A5D4FFF1
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Radiological profile of anemia on unenhanced MDCT of the thorax.
Périodique
European Radiology
Auteur(s)
Kamel E.M., Rizzo E., Duchosal M.A., Duran R., Goncalves-Matoso V., Schnyder P., Qanadli S.D.
ISSN
0938-7994
Statut éditorial
Publié
Date de publication
2008
Peer-reviewed
Oui
Volume
18
Numéro
9
Pages
1863-1868
Langue
anglais
Résumé
Our aim was to investigate the diagnostic value of unenhanced MDCT in anemic patients. Fifty consecutive patients with proven anemia and 50 nonanemic matched group for age, sex and body mass index were evaluated. In either group, hemoglobin levels were assessed no more than 24 h from an unenhanced CT of the thorax. For each patient, the presence of a hyperattenuating aortic wall (aortic ring sign) and/or dense interventricular septum (subjective parameters) were identified by two radiologists who were blinded to the laboratory findings. Furthermore, the aortic CT attenuation values (objective parameter) were also obtained and correlated with the hemoglobin levels. The sensitivity and specificity in detecting anemia were calculated for each variable, and ROC analysis was generated for subjective and objective parameters. Subjective image analysis revealed that the aortic ring sign was more sensitive than the interventricular septum sign for anemia detection (84% vs. 72%), whereas this latter sign was more specific (100% vs. 92%). A good correlation (r = 0.60) was observed between the aortic CT attenuation values and the hemoglobin levels in the whole study population. Using a threshold of < or = 35 HU for anemia diagnosis, the sensitivity and specificity of aortic CT attenuation value were 84% and 94%, respectively, with the largest area under the curve (0.89) among all diagnostic criteria. However, the best trade-off between sensitivity (80%) and specificity (100%) was obtained from combining both subjective and objective analysis. Interpreting anemia upon unnenhanced MDCT of the thorax is quite feasible. A diagnostic approach that considers both subjective and objective analysis offers the best trade-off between sensitivity and specificity.
Mots-clé
Adult, Aged, Aged, 80 and over, Anemia, Aortography, Contrast Media, Female, Heart Septum, Humans, Male, Middle Aged, Radiography, Thoracic, Reproducibility of Results, Sensitivity and Specificity, Single-Blind Method, Tomography, X-Ray Computed, Young Adult
Pubmed
Web of science
Création de la notice
04/06/2008 11:04
Dernière modification de la notice
20/08/2019 17:23
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