High-field dissolution dynamic nuclear polarization of [1-(13)C]pyruvic acid.

Détails

ID Serval
serval:BIB_F70A128649AC
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
High-field dissolution dynamic nuclear polarization of [1-(13)C]pyruvic acid.
Périodique
Physical Chemistry Chemical Physics : Pccp
Auteur(s)
Yoshihara H.A., Can E., Karlsson M., Lerche M.H., Schwitter J., Comment A.
ISSN
1463-9084 (Electronic)
ISSN-L
1463-9076
Statut éditorial
Publié
Date de publication
2016
Peer-reviewed
Oui
Volume
18
Numéro
18
Pages
12409-12413
Langue
anglais
Notes
Publication types: Journal ArticlePublication Status: ppublish
Résumé
[1-(13)C]pyruvate is the most widely used hyperpolarized metabolic magnetic resonance imaging agent. Using a custom-built 7.0 T polarizer operating at 1.0 K and trityl radical-doped [1-(13)C]pyruvic acid, unextrapolated solution-state (13)C polarization greater than 60% was measured after dissolution and rapid transfer to a spectrometer magnet, demonstrating the signal enhancement attainable using optimized hardware. Slower rates of polarization under these conditions can be largely overcome with higher radical concentrations.
Pubmed
Web of science
Création de la notice
03/05/2016 17:31
Dernière modification de la notice
20/08/2019 17:23
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