Article: article from journal or magazin.
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Inégalité des sexes face au cancer en urologie [Gender disparities in urologic cancers].
Revue Médicale Suisse
Publication types: English Abstract ; Journal Article ; ReviewPublication Status: ppublish
The purpose of the present review is to summarize the current knowledge on the impact of gender on urological cancers. There is a discrepancy in the incidence of urothelial and kidney cancers, with a higher prediction for male patients. Men have a three-times greater risk of developing bladder cancer compared to women, but female gender has been identified as an independent adverse prognostic factor for both disease recurrence and progression. At diagnosis, men with renal cell carcinoma present more often with larger tumors and higher stage and grade disease compared to females. Smoking habits, tumor biology, sex steroid hormones, genetic differences and social behavior may be the main drivers of gender disparities. Therefore, the inclusion of this variable in validated prognostic tables and nomograms should be concretely discussed.
Disease Progression, Female, Health Status Disparities, Humans, Incidence, Male, Neoplasm Grading, Neoplasm Recurrence, Local, Neoplasm Staging, Prognosis, Risk Factors, Sex Factors, Urologic Neoplasms/epidemiology, Urologic Neoplasms/pathology
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