Habitual Preference for the Nondrug Reward in a Drug Choice Setting.

Details

Serval ID
serval:BIB_F5AED44C81BB
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Habitual Preference for the Nondrug Reward in a Drug Choice Setting.
Journal
Frontiers in behavioral neuroscience
Author(s)
Vandaele Y., Guillem K., Ahmed S.H.
ISSN
1662-5153 (Print)
ISSN-L
1662-5153
Publication state
Published
Issued date
2020
Peer-reviewed
Oui
Volume
14
Pages
78
Language
english
Notes
Publication types: Journal Article
Publication Status: epublish
Abstract
For adaptive and efficient decision making, it must be possible to select between habitual alternative courses of action. However, research in rodents suggests that, even in the context of simple decision-making, choice behavior remains goal-directed. In contrast, we recently found that during discrete trial choice between cocaine and water, water-restricted rats preferred water and this preference was habitual and inflexible (i.e., resistant to water devaluation by satiation). Here we sought to test the reproducibility and generality of this surprising finding by assessing habitual control of preference for saccharin over cocaine in non-restricted rats. Specifically, after the acquisition of preference for saccharin, saccharin was devalued and concurrent responding for both options was measured under extinction. As expected, rats responded more for saccharin than for cocaine during extinction, but this difference was unaffected by saccharin devaluation. Together with our previous research, this result indicates that preference for nondrug alternatives over cocaine is under habitual control, even under conditions that normally support goal-directed control of choice between nondrug options. The possible reasons for this difference are discussed.
Keywords
choice, cocaine, goal-directed, habit, saccharin, sweetness
Pubmed
Web of science
Open Access
Yes
Create date
25/06/2020 16:53
Last modification date
30/12/2023 8:07
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