Article: article from journal or magazin.
Case report (case report): feedback on an observation with a short commentary.
Cervical nerve root synovial sarcoma in a child with chromosomal (X;18) translocation. Case report and review of the literature.
Publication types: Case Reports ; Journal Article ; Review - Publication Status: ppublish
We report on an 11-year-old female with a history of cervicobrachialgia and progressive weakness of the right arm. Cervical spine MRI showed an enhancing heterogeneous intradural mass occupying the right C6-C7 foramen. She underwent a right C6-C7 foraminotomy with a complete macroscopic removal of the lesion. Pathological examination revealed a synovial sarcoma. Treatment was completed by chemotherapy and proton radiotherapy, and the girl remained free of symptoms for 3 years. After appearance of new symptoms, a local recurrence was confirmed, and despite aggressive treatment with salvage chemotherapy and radiotherapy, the disease progressed beyond medical control, and the child died, 6 years after diagnosis. Early recognition of this rare entity compared to its more benign differential diagnosis is crucial, as an aggressive management is needed.
Cervical Vertebrae, Child, Chromosomes, Human, Pair 18, Chromosomes, Human, X, Female, Humans, Peripheral Nervous System Neoplasms, Sarcoma, Synovial, Spinal Nerve Roots, Translocation, Genetic
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