Poly(m6A) tails stabilize transcripts.

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Serval ID
serval:BIB_F4D6B97820E7
Type
Article: article from journal or magazin.
Publication sub-type
Editorial
Collection
Publications
Institution
UNIL/CHUV
Title
Poly(m6A) tails stabilize transcripts.
Journal
Molecular cell
Author(s)
Lavergne G., Roignant J.Y.
ISSN
1097-4164 (Electronic)
ISSN-L
1097-2765
Publication state
Published
Issued date
02/06/2022
Peer-reviewed
Oui
Volume
82
Number
11
Pages
1979-1980
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't ; Comment
Publication Status: ppublish
Abstract
Viegas et al. (2022) discover that in Trypanosoma brucei the poly(A) tails of the variant surface glycoprotein (VSG) transcripts are methylated, a mechanism that stabilizes these transcripts and ensures protection against the immune response in mammals.
Keywords
Animals, Mammals, Membrane Glycoproteins, Poly A/genetics, RNA, Messenger/genetics, Trypanosoma brucei brucei/genetics, Variant Surface Glycoproteins, Trypanosoma/genetics
OAI-PMH
oai:serval.unil.ch:BIB_F4D6B97820E7
DOI
10.1016/j.molcel.2022.05.017
Pubmed
35659324
Web of science
000822391900005
Create date
07/06/2022 8:49
Last modification date
14/03/2024 8:09
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