In vitro analysis of the ability of Trichophyton rubrum to become resistant to terbinafine

Osborne,  C. S.; Hofbauer,  B.; Favre,  B.; Ryder,  N. S.

doi:10.1128/AAC.47.11.3634-3636.2003

In vitro analysis of the ability of Trichophyton rubrum to become resistant to terbinafine

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Serval ID

serval:BIB_F452A2D9A709

Type

Article: article from journal or magazin.

Collection

Publications

Institution

UNIL/CHUV

Title

In vitro analysis of the ability of Trichophyton rubrum to become resistant to terbinafine

Journal

Antimicrobial Agents and Chemotherapy

Author(s)

Osborne C. S., Hofbauer B., Favre B., Ryder N. S.

ISSN

0066-4804 (Print)

Publication state

Published

Issued date

11/2003

Volume

Number

Pages

3634-6

Notes

Journal Article --- Old month value: Nov

Abstract

In this study, we have investigated in vitro the resistance frequency and development of resistance to terbinafine of Trichophyton rubrum. Results demonstrated that naturally occurring mutants are rare and that T. rubrum appears to have little capacity to develop resistance to terbinafine even after prolonged exposure.

Keywords

Antifungal Agents/*pharmacology Colony Count, Microbial Culture Media Drug Resistance, Fungal/*genetics Naphthalenes/*pharmacology Phenotype Trichophyton/*drug effects/genetics

OAI-PMH

oai:serval.unil.ch:BIB_F452A2D9A709

DOI

10.1128/AAC.47.11.3634-3636.2003

Pubmed

14576134

Web of science

000186311400044

Open Access

Yes

Create date

25/01/2008 17:32