Neural dissociation of phonological and visual attention span disorders in developmental dyslexia: FMRI evidence from two case reports.

Détails

ID Serval
serval:BIB_F402A69256CD
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Etude de cas (case report): rapporte une observation et la commente brièvement.
Collection
Publications
Titre
Neural dissociation of phonological and visual attention span disorders in developmental dyslexia: FMRI evidence from two case reports.
Périodique
Brain and Language
Auteur(s)
Peyrin C., Lallier M., Démonet J.F., Pernet C., Baciu M., Le Bas J.F., Valdois S.
ISSN
1090-2155 (Electronic)
ISSN-L
0093-934X
Statut éditorial
Publié
Date de publication
2012
Peer-reviewed
Oui
Volume
120
Numéro
3
Pages
381-394
Langue
anglais
Notes
Publication types: Case Reports ; Journal Article ; Research Support, Non-U.S. Gov'tPublication Status: ppublish
Résumé
A dissociation between phonological and visual attention (VA) span disorders has been reported in dyslexic children. This study investigates whether this cognitively-based dissociation has a neurobiological counterpart through the investigation of two cases of developmental dyslexia. LL showed a phonological disorder but preserved VA span whereas FG exhibited the reverse pattern. During a phonological rhyme judgement task, LL showed decreased activation of the left inferior frontal gyrus whereas this region was activated at the level of the controls in FG. Conversely, during a visual categorization task, FG demonstrated decreased activation of the parietal lobules whereas these regions were activated in LL as in the controls. These contrasted patterns of brain activation thus mirror the cognitive disorders' dissociation. These findings provide the first evidence for an association between distinct brain mechanisms and distinct cognitive deficits in developmental dyslexia, emphasizing the importance of taking into account the heterogeneity of the reading disorder.
Mots-clé
Acoustic Stimulation, Adult, Attention/physiology, Attention Deficit Disorder with Hyperactivity/physiopathology, Cognition Disorders/physiopathology, Dyslexia/physiopathology, Female, Frontal Lobe/physiopathology, Humans, Magnetic Resonance Imaging, Male, Neuropsychological Tests, Parietal Lobe/physiopathology, Pattern Recognition, Visual/physiology, Phonetics, Photic Stimulation, Reading, Young Adult
Pubmed
Web of science
Création de la notice
24/03/2013 0:06
Dernière modification de la notice
03/03/2018 22:43
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