Antifungal principles of Baccharis pedunculata.

Détails

ID Serval
serval:BIB_F3E35DCE7F37
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Antifungal principles of Baccharis pedunculata.
Périodique
Planta Medica
Auteur(s)
Rahalison L., Benathan M., Monod M., Frenk E., Gupta M.P., Solis P.N., Fuzzati N., Hostettmann K.
ISSN
0032-0943
Statut éditorial
Publié
Date de publication
08/1995
Peer-reviewed
Oui
Volume
61
Numéro
4
Pages
360-362
Langue
anglais
Notes
Publication types: Letter ; Research Support, Non-U.S. Gov't - Publication Status: ppublish
Résumé
Four compounds including a flavone, an acetylenic lactone, a prenylated coumarin, and a 3-methyl ether flavone were isolated from the dichloromethane leaf extract of Baccharis pedunculata (Mill.) Cabr. (Asteraceae). The latter three compounds were identified to be responsible for the antifungal activity against some human pathogenic and phytopathogenic fungi. The most active compound, lachnophyllum lactone, an acetylenic lactone, showed a very high toxicity (LD50 2 micrograms/ml) against human keratinocytes.
Mots-clé
Antifungal Agents, Cell Survival, Cells, Cultured, Coumarins, Flavonoids, Fungi, Humans, Keratinocytes, Lactones, Microbial Sensitivity Tests, Plant Extracts, Plant Leaves, Structure-Activity Relationship
Pubmed
Web of science
Création de la notice
25/01/2008 17:47
Dernière modification de la notice
03/03/2018 22:43
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