Continuous assessment of electrical epileptic activity in acute stroke.

Détails

ID Serval
serval:BIB_F37BE1E182B8
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Continuous assessment of electrical epileptic activity in acute stroke.
Périodique
Neurology
Auteur(s)
Carrera E., Michel P., Despland P.A., Maeder-Ingvar M., Ruffieux C., Debatisse D., Ghika J., Devuyst G., Bogousslavsky J.
ISSN
1526-632X[electronic]
Statut éditorial
Publié
Date de publication
2006
Peer-reviewed
Oui
Volume
67
Numéro
1
Pages
99-104
Langue
anglais
Résumé
OBJECTIVE: To determine the incidence and risk factors of electrical seizures and other electrical epileptic activity using continuous EEG (cEEG) in patients with acute stroke. METHODS: One hundred consecutive patients with acute stroke admitted to our stroke unit underwent cEEG using 10 electrodes. In addition to electrical seizures, repetitive focal sharp waves (RSHWs), repetitive focal spikes (RSPs), and periodic lateralized epileptic discharges (PLEDs) were recorded. RESULTS: In the 100 patients, cEEG was recorded for a mean duration of 17 hours 34 minutes (range 1 hour 12 minutes to 37 hours 10 minutes). Epileptic activity occurred in 17 patients and consisted of RSHWs in seven, RSPs in seven, and PLEDs in three. Electrical seizures occurred in two patients. On univariate Cox regression analysis, predictors for electrical epileptic activity were stroke severity (high score on the National Institutes of Health Stroke Scale) (hazard ratio [HR] 1.12; p = 0.002), cortical involvement (HR 5.71; p = 0.021), and thrombolysis (HR 3.27; p = 0.040). Age, sex, stroke type, use of EEG-modifying medication, and cardiovascular risk factors were not predictors of electrical epileptic activity. On multivariate analysis, stroke severity was the only independent predictor (HR 1.09; p = 0.016). CONCLUSION: In patients with acute stroke, electrical epileptic activity occurs more frequently than previously suspected.
Mots-clé
Adult, Aged, Aged, 80 and over, Brain/pathology, Brain/physiopathology, Brain Mapping, Electroencephalography/methods, Epilepsy/epidemiology, Epilepsy/physiopathology, Female, Humans, Incidence, Male, Middle Aged, Proportional Hazards Models, Prospective Studies, Risk Factors, Sex Factors, Stroke/epidemiology, Stroke/physiopathology, Time Factors
Pubmed
Web of science
Création de la notice
25/01/2008 12:45
Dernière modification de la notice
03/03/2018 22:42
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