Demand on verbal working memory delays haemodynamic response in the inferior prefrontal cortex.

Détails

ID Serval
serval:BIB_F36A76B74BE3
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Demand on verbal working memory delays haemodynamic response in the inferior prefrontal cortex.
Périodique
Human Brain Mapping
Auteur(s)
Thierry G., Ibarrola D., Démonet J.F., Cardebat D.
ISSN
1065-9471 (Print)
ISSN-L
1065-9471
Statut éditorial
Publié
Date de publication
2003
Peer-reviewed
Oui
Volume
19
Numéro
1
Pages
37-46
Langue
anglais
Notes
Publication types: Comparative Study ; Journal ArticlePublication Status: ppublish. PDF type: Research Article
Résumé
Event-related functional magnetic resonance imaging was used to test the involvement of the inferior prefrontal cortex in verbal working memory. Pairs of French nouns were presented to ten native French speakers who had to make semantic or grammatical gender decisions. Verbal working memory involvement was manipulated by making the categorization of the second noun optional. Decisions could be made after processing the first noun only (RELEASE condition) or after processing the two nouns (HOLD condition). Reaction times suggested faster processing for gender than for semantic category in RELEASE. Despite the absence of anatomical difference across tasks and conditions in the wide activated network, the haemodynamic response peak latencies of the inferior prefrontal cortex were significantly delayed in HOLD versus RELEASE while no such peak delay was observed in the superior temporal gyrus. Interestingly, this pattern did not interact with language tasks. This study shows that cognitive manipulation can influence haemodynamic time-course and suggests that the main cognitive process determining inferior prefrontal activation is verbal working memory rather than specific linguistic processes such as grammatical or semantic analysis.
Mots-clé
Acoustic Stimulation/methods, Adult, Analysis of Variance, Brain Mapping/methods, Female, Hemodynamics/physiology, Humans, Magnetic Resonance Imaging/methods, Magnetic Resonance Imaging/statistics & numerical data, Male, Memory/physiology, Prefrontal Cortex/physiology, Semantics
Pubmed
Web of science
Création de la notice
24/03/2013 19:35
Dernière modification de la notice
20/08/2019 17:20
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