Autogreffe de cellules souches hématopoïétiques périphériques dans le cadre du traitement d'hémopathies malignes. Partie I: patients [Autologous transplantation of peripheral blood hematopoietic stem cells in the treatment of hematological malignancies. I: patients]

Détails

ID Serval
serval:BIB_F203A020B930
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Autogreffe de cellules souches hématopoïétiques périphériques dans le cadre du traitement d'hémopathies malignes. Partie I: patients [Autologous transplantation of peripheral blood hematopoietic stem cells in the treatment of hematological malignancies. I: patients]
Périodique
Schweizerische medizinische Wochenschrift
Auteur(s)
Medinger P., Tissot J.D., Nicoloso de Faveri G., Kovacsovics T.J., Perey L., Schneider P., Zwicky C.
ISSN
0036-7672
Statut éditorial
Publié
Date de publication
04/2000
Peer-reviewed
Oui
Volume
130
Numéro
13
Pages
478-84
Langue
français
Notes
Publication types: English Abstract ; Journal Article - Publication Status: ppublish
Résumé
61 autologous transplantations for haematological malignancies have been performed with peripheral blood stem cells in 60 patients. 26 grafts were performed for non-Hodgkin's lymphoma (18 patients were transplanted in first remission, 8 patients after progression or relapse), 13 for multiple myeloma, 7 for Hodgkin's disease and 10 for acute myeloid leukaemia. One patient died from thrombosis of the portal vein. 38 patients were in complete remission 29 months (extremes: 14-44) after transplantation. 21 of 60 patients progressed or relapsed after transplantation, and 14 died. No death was attributed to graft failure, infection or haemorrhage. In conclusion, transplantation with peripheral blood stem cells is well tolerated, has a low toxicity rate, and can be used safely for patients with haematological malignancies.
Mots-clé
Adolescent, Adult, Aged, Female, Follow-Up Studies, Hematologic Neoplasms/therapy, Hematopoietic Stem Cell Transplantation, Humans, Leukemia, Myeloid, Acute/blood, Lymphoma, Non-Hodgkin/blood, Male, Middle Aged, Multiple Myeloma/blood, Retrospective Studies, Transplantation, Autologous
Pubmed
Web of science
Création de la notice
25/01/2008 16:34
Dernière modification de la notice
03/03/2018 22:39
Données d'usage