Malignes Melanom der Haut. [Malignant melanoma of the skin]

Détails

ID Serval
serval:BIB_F12976F01826
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
Malignes Melanom der Haut. [Malignant melanoma of the skin]
Périodique
Therapeutische Umschau
Auteur(s)
Burg  G., Dummer  R., Cavegn  B., Panizzon  R.
ISSN
0040-5930 (Print)
Statut éditorial
Publié
Date de publication
12/1993
Volume
50
Numéro
12
Pages
822-7
Notes
English Abstract
Journal Article
Review --- Old month value: Dec
Résumé
The frequency of malignant melanoma is increasing worldwide and comprises in middle Europe about 10 per 100,000 inhabitants per year; it is fatal in each forth or fifth patient. Risk factors may be endogenous, like fair skin with high sensitivity for sun exposure and the presence of many, possibly atypical ('dysplastic') naevi, or exogenous, e.g. excessive exposure to ultraviolet light. The superficial spreading malignant melanoma is the most common form of clinical manifestation. Applying the A (asymmetry), B (border), C (color), D (diameter), E (elevation) rule is a reliable help for making the diagnosis of malignant melanoma. The differential diagnosis besides various naevi comprises a wide spectrum of pigmented new formations of the skin. Classification of malignant melanoma follows the TNM system; spread, tumor thickness and/or level of infiltration are appropriate parameters. The most important prognostic parameter is tumor thickness, which results in 10-year survival time of only 30% if it exceeds 3 mm. The therapy of malignant melanoma is performed by excision with margins between 1 and 3 cm, depending on tumor thickness. Frequency and type of investigations for follow-up controls depend on the risk for metastases, i.e. on tumor thickness. Best prevention is achieved by avoiding excessive exposure to ultraviolet light, especially during childhood, and by early diagnosis of thin melanoma.
Mots-clé
Combined Modality Therapy Diagnosis, Differential Humans Melanoma/*diagnosis/pathology/surgery Neoplasm Staging Neoplasms, Radiation-Induced/*diagnosis/pathology/surgery Prognosis Risk Factors Skin/pathology Skin Neoplasms/*diagnosis/pathology/surgery Ultraviolet Rays/*adverse effects
Pubmed
Création de la notice
25/01/2008 17:55
Dernière modification de la notice
03/03/2018 22:38
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