Etude de l'interaction sperme-glaire en cycles controles: faisabilite d'une nouvelle approche. [Study of sperm-cervical mucus interaction in controlled cycles: feasibility of a new approach]

Détails

ID Serval
serval:BIB_F0CCE5EC1A0A
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Etude de l'interaction sperme-glaire en cycles controles: faisabilite d'une nouvelle approche. [Study of sperm-cervical mucus interaction in controlled cycles: feasibility of a new approach]
Périodique
Contracept Fertil Sex
Auteur(s)
Freitas  S. A., Glissant  A., Schwab  B., Fanchin  R., Frydman  R., de Ziegler  D.
ISSN
1165-1083
Statut éditorial
Publié
Date de publication
08/1994
Volume
22
Numéro
7-8
Pages
455-8
Notes
English Abstract
Journal Article --- Old month value: Jul-Aug
Résumé
We report a prospective trial of in vitro sperm-mucus penetration test performed in hormonally controlled environment. To enhance the quality of the cervical mucus (CM), prevent spontaneous ovulation and to eliminate the possibility that results may be biased solely because of CM inadequacy, we conceived a 28-day physiological hormonal replacement regimen. For this women received oral estradiol valerate (E2-V) (4 mg/day) from cycle 1 to 28. CM was collected on days 13 (n = 17), 14 (n = 38) or 15 (n = 16), according to patients' individual preferences. The in vitro sperm-mucus penetration test was performed approximately 30 minutes later. On the same day, measurements of P and E2 levels were done to eliminate the possibility of spontaneous ovulation. Plasma E2 on the day of testing were 220 +/- 100 pg/ml (mean +/- SD). In all patients, except 4, P levels were low (< 1 ng/ml) on the day of the test. Our results indicate that a hormonal preparation with E2/P can be clinically useful for preventing spontaneous ovulation and reliably assuring CM quality when sperm/mucus penetration tests are performed.
Mots-clé
Administration, Oral Bias (Epidemiology) *Cervix Mucus Estradiol/*analogs & derivatives/blood/therapeutic use Estrogens, Conjugated (USP)/blood/*therapeutic use Female Humans Infertility/blood/*therapy Male Ovulation Induction/*methods Progesterone/blood/*therapeutic use Prospective Studies *Sperm-Ovum Interactions
Pubmed
Web of science
Création de la notice
28/02/2008 12:37
Dernière modification de la notice
03/03/2018 22:37
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