A light in the cognitive fog?

Détails

ID Serval
serval:BIB_F0C311769084
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Editorial
Collection
Publications
Titre
A light in the cognitive fog?
Périodique
Antiviral Therapy
Auteur(s)
Cavassini M., Du Pasquier R.A.
ISSN
2040-2058 (Electronic)
ISSN-L
1359-6535
Statut éditorial
Publié
Date de publication
2013
Peer-reviewed
Oui
Volume
18
Numéro
2
Pages
149-151
Langue
anglais
Notes
Publication types: Journal ArticlePublication Status: ppublish. PDF type: Commentary
Résumé
HIV escape in the central nervous system (CNS) despite undetectable viral load in the plasma has been observed and may contribute to HIV-associated neurocognitive disorders. Favouring the use of HIV drugs with a good penetration into the CNS has been advocated, leading to the establishment of the CNS penetration-effectiveness (CPE) score. However, the relevance of this score is not fully established. Ciccarelli et al. compared two versions of the CPE scores in their capacity to predict cognitive dysfunction in HIV-infected individuals. The revised CPE score, but not the original one, showed an improved association with cognitive impairment. Prospective studies are warranted to assess the validity of the CPE score.
Pubmed
Web of science
Création de la notice
08/04/2013 15:46
Dernière modification de la notice
03/03/2018 22:37
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