Onion and garlic use and human cancer

Détails

ID Serval
serval:BIB_F0660F3BEFE7
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Onion and garlic use and human cancer
Périodique
American Journal of Clinical Nutrition
Auteur(s)
Galeone  Carlotta, Pelucchi  Claudio, Levi  Fabio, Negri  Eva, Franceschi  Silvia, Talamini  Renato, Giacosa  Attilio, La Vecchia  Carlo
ISSN
0002-9165
Statut éditorial
Publié
Date de publication
2006
Volume
84
Numéro
5
Pages
1027-1032
Notes
SAPHIRID:59654 --- Old url value: http://www.ajcn.org/cgi/content/full/84/5/1027
Résumé
BACKGROUND: Interest in the potential benefits of allium vegetables, in particular, onion (Allium cepa) and garlic (Allium sativum), has its origin in antiquity, but the details of these benefits are still open to discussion. OBJECTIVE: We investigated the role of allium vegetables in the etiology of various neoplasms. Previous data are scanty and are based mainly on Chinese studies. DESIGN: Using data from an integrated network of Italian and Swiss case-control studies, we analyzed the relation between frequency of onion and garlic use and cancer at several sites. We calculated odds ratios (ORs) by using multivariate logistic regression models that were adjusted for energy intake and other major covariates. RESULTS: Consumption of onions varied between 0-14 and 0-22 portions/wk among cases and controls, respectively. The multivariate ORs for the highest category of onion and garlic intake were, respectively, 0.16 and 0.61 for cancer of the oral cavity and pharynx, 0.12 and 0.43 for esophageal cancer, 0.44 and 0.74 for colorectal cancer, 0.17 and 0.56 for laryngeal cancer, 0.75 and 0.90 for breast cancer, 0.27 and 0.78 for ovarian cancer, 0.29 and 0.81 for prostate cancer, and 0.62 and 0.69 for renal cell cancer. CONCLUSIONS: This uniquely large data set from southern European populations shows an inverse association between the frequency of use of allium vegetables and the risk of several common cancers. Allium vegetables are a favorable correlate of cancer risk in Europe. [Authors]
Mots-clé
Diet , Garlic , Neoplasms , Onions
Pubmed
Web of science
Création de la notice
04/03/2008 15:58
Dernière modification de la notice
03/03/2018 22:36
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