Vision after early-onset lesions of the occipital cortex: II. Physiological studies.

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Serval ID
serval:BIB_F020CB1D58EC
Type
Article: article from journal or magazin.
Publication sub-type
Letter (letter): Communication to the publisher.
Collection
Publications
Institution
Title
Vision after early-onset lesions of the occipital cortex: II. Physiological studies.
Journal
Neural Plasticity
Author(s)
Knyazeva M.G., Maeder P., Kiper D.C., Deonna T., Innocenti G.M.
ISSN
1687-5443[electronic]
Publication state
Published
Issued date
2002
Volume
9
Number
1
Pages
27-40
Language
english
Notes
Publication types: Comment ; Journal Article ; Research Support, Non-U.S. Gov't - Publication Status: ppublish
Abstract
In one of two patients (MS and FJ) with bilateral, early-onset lesion of the primary visual cortex, Kiper et al. (2002) observed a considerable degree of functional recovery. To clarify the physiological mechanisms involved in the recovery, we used fMRI and quantitative EEG to study both patients. The fMRI investigations indicated that in both patients, isolated islands of the primary visual cortex are functioning, in the right hemisphere in MS and in the left in FJ. The functional recovery observed in MS roughly correlated with the functional maturation of interhemispheric connections and might reflect the role of corticocortical connectivity in visual perception. The functionality of interhemispheric connections was assessed by analyzing the changes in occipital inter-hemispheric coherence of EEG signals (ICoh) evoked by moving gratings. In the patient MS, this ICoh response was present at 7:11 y and was more mature at 9:2 y. In the more visually impaired patient, FJ, a consistent increase in ICoh to visual stimuli could not be obtained, possibly because of the later occurrence of the lesion.
Keywords
Adolescent, Age of Onset, Child, Electroencephalography, Female, Form Perception, Humans, Magnetic Resonance Imaging, Male, Neuronal Plasticity, Photic Stimulation, Recovery of Function, Vision, Ocular, Visual Cortex
Pubmed
Open Access
Yes
Create date
11/04/2008 8:23
Last modification date
20/08/2019 16:17
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