Metastatic choroidal paraganglioma.

Détails

ID Serval
serval:BIB_EF4F7BAAA873
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Etude de cas (case report): rapporte une observation et la commente brièvement.
Collection
Publications
Titre
Metastatic choroidal paraganglioma.
Périodique
Ophthalmology
Auteur(s)
Schalenbourg A., Moulin A., Guillou L., Zografos L.
ISSN
1549-4713 (Electronic)
ISSN-L
0161-6420
Statut éditorial
Publié
Date de publication
2011
Peer-reviewed
Oui
Volume
118
Numéro
11
Pages
2238-2241
Langue
anglais
Notes
Publication types: Case Reports ; Journal Article
Résumé
PURPOSE: To describe a patient with metastatic choroidal paraganglioma that was locally controlled with radiotherapy.
DESIGN: Interventional clinicopathologic case report.
PARTICIPANT: One patient with metastatic choroidal paraganglioma.
METHODS: Interventional clinicopathologic case report and systematic search of the literature.
MAIN OUTCOME MEASURES: Description of clinicopathologic features, treatment methods, and outcome.
RESULTS: A 50-year-old man had a nonpigmented atypical choroidal mass with secondary retinal detachment in the left eye. After incisional biopsy, the diagnosis of paraganglioma was established. Metastatic work-up revealed vertebral, mediastinal, and pulmonary metastases of a nonsecretory, malignant paraganglioma without tracer uptake. The primary tumor was not identified. The ocular tumor regressed after stereotaxic radiotherapy. Two years later, recurrent lesions developed in the contralateral eye, which also was irradiated.
CONCLUSIONS: Malignant paraganglioma can metastasize in the choroid and should be included in the differential diagnosis of a nonpigmented choroidal mass. Stereotaxic radiation therapy is an effective treatment method. To the authors' knowledge, this is the first report of a patient with choroidal paraganglioma.
FINANCIAL DISCLOSURE(S): The author(s) have no proprietary or commercial interest in any materials discussed in this article.
Mots-clé
Choroid Neoplasms/radiotherapy, Choroid Neoplasms/secondary, Humans, Lung Neoplasms/secondary, Male, Mediastinal Neoplasms/secondary, Middle Aged, Paraganglioma/radiotherapy, Paraganglioma/secondary, Spinal Neoplasms/secondary, Visual Acuity/physiology
Pubmed
Web of science
Création de la notice
08/11/2011 10:02
Dernière modification de la notice
19/03/2018 11:57
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